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    Bioprocess Technology ZHAW

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    We can help you
    • develop efficient and product-tailored bioprocesses
    • identify, monitor and control the critical key parameters of your process
    • implement automated IoT infrastructures for fermentation labs
    • establish smart PAT concepts and cell-based analytics
    • exploit bioprocess data via end-to-end integrated computational workflows
    • advance to intensified and industry-compliant process configurations (high-cell-density fedbatch & continuous cultures)
    • use alternative and sustainable host systems (incl. microalgae, biotech food platforms, whole-cell products, vaccine strains,...) 
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    Competencies
    • Bioprocessing
    • Automation
    • Analytics
    • Data Science
    • Drug Development
    • Biologics
    Competencies (detailed)
    • Microbial cell culture (E. coli, P. pastoris, etc)
    • Microalgae biotechnology for high-value compounds
    • Prototype development and testing
    • Biotech production platforms for novel food ingredients
    • Integrated drug delivery concepts for biologics
    • Digital technologies for process improvement: data visualization and advanced modeling
    • Process analytical technologies (PAT) for process monitoring
    • Biomass- and cell-focussed real-time monitoring concepts
    • Bioconjugation and fusion proteins for pharmaceutical biotech
    Infrastructure
    • Bioreactors
    • Biosafety Level 2
    • Cell Culture
    • Flow Cytometry
    • Microscopy
    • Sensors
    • Spectroscopy
    • Strain Collection
    Infrastructure (detailed)
    • Benchtop bioreactors (0.5 - 5L)
    • CIP/SIP automated bioreactors (20L/50L)
    • Photobioreactors for photo-/hetero-/mixotrophic cultivation of microalgae etc.
    • Fully integrated and flexibly programmable process management and control software
    • Inline/Online sensors (Impedance, OD, Fluorescence, Raman)
    • Automated sampling system (liquid sampling, filtration, storage, handover to analyzer)
    • Online monitoring of shake-flask cultures
    • Cell culture test systems for bioassays (e.g. cytoadhesion and invasion)
    • Flow cytometer for combined light scatter analysis and in-flow imaging
    • Fluorescence microscopy
    • Atomic force microscopy (AFM)
    • AR- and VR-supported visualization and workflow-guidance (MS Hololens)
    Biotechnet platforms
    Biomanufacturing
    Data Science
    Biocatalysis and Biosynthesis
    Group leader
    Lukas Neutsch
    Academic institution
    ZHAW - Zurich University of Applied Sciences
    Location

    Grüentalstrasse 14, Wädenswil, Switzerland

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