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    Molecular Biology and Biochemistry Verified listing Verified listing

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    We can help you

    Our group conducts application-oriented research in the fields of molecular biology and biochemistry, aiming at the development of novel therapeutics and tools for diagnostics and the identification of new molecular targets for drugs.

    We have many years of expertise in the fields of antibiotic resistance and antimicrobial agents, characterization of microorganisms, cancer research and protein engineering.

    One focus is on DNA replication and DNA repair proteins, as these represent interesting targets in cancer therapy and can also be used as tools in diagnostics and bioanalytics.

    Another focus is on the development of novel antimicrobial agents, including those based on bacteriophage proteins, in order to counteract the current antibiotic resistance problem.
     

    Competencies
    • Antibiotics
    • Biologics
    • Diagnostics
    • Drug Development
    • In Vitro Assays
    Competencies (detailed)
    • Identification and characterization of microorganisms
    • Cloning and production of recombinant proteins in E. coli, yeast cells, insect cells, CHO and HEK cells
    • Purification and functional characterization of proteins
    • Protein engineering
    • Development of in vitro assays
    • Antimicrobial agents
    • qPCR-based analyses
    • Production of stable cell lines and knockout cell lines
    • Cell viability tests
    Infrastructure
    • Biosafety Level 2
    • Cell Culture
    • Chromatography
    • Microscopy
    • Purification
    • Strain Collection
    Group leader
    Mathias Schmelcher
    Kerstin Gari
    Academic institution
    ZHAW ICBT - Zurich University of Applied Sciences - Institute for Chemistry and Biotechnology
    Location
    • Einsiedlerstrasse 31, 8820 Wädenswil, Switzerland

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