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    Cell Cultivation Techniques

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    We can help you
    • To establish and optimize plant cell lines for the production of bioactive ingredients and additives for the pharmaceutical, cosmetics and food sectors
    • To develop biotechnological production processes based on plant, insect and mammalian cells (including stem cells) up to pilot scale by
      • High throughput screening of production clones and selection of production cell lines

      • Medium optimizations

      • Process parameter scouting

      • Microcarrier screening and cultivations

    • To intensify upstream processes by
      • Implementing single-use technologies

      • Developing N-1 perfusions

      • Realizing super-intensified inoculum productions, high-seed fed-batch, concentrated fed-batch and continuous productions

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    Competencies
    • Bioprocessing
    • Analytics
    • Biologics
    • Cell and Tissue Engineering
    • Drug Development
    • Food Research
    • Stem Cells
    Competencies (detailed)
    • Cell cultivation techniques
    • Cell cultures with primary cells and cell lines
    • Mammalian cell culture (CHO-S, CHO-K1, HEK293F, HEK293T, etc)
    • Cell therapeutics based on hMSCs and iPSCs
    • Biotherapeutics (mAbs, vaccines)
    • Process Development
    • Biomass- and cell-focussed real-time monitoring concepts
    • Cellular agriculture
    • Biotech production platforms for novel food ingredients
    • Plant cell culture-based extracts for cosmetics industry
    • Plant cell culture-based recombinant proteins and secondary metabolites
    • Cosmeceuticals
    • Lab grown meat
    • Single-use technologies
    • Training
    Biotechnet platforms
    Single Use Technology
    Biocatalysis and Biosynthesis
    Training for Pharma / Biotech
    Connect with us

      Group leader
      Regine Eibl
      Academic institution
      ZHAW - Zurich University of Applied Sciences
      Location

      Grüentalstrasse 14, Wädenswil, Switzerland

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      Infrastructure
      • Bioreactors
      • Cell Culture
      • Biobank
      • Biosafety Level 2
      • Flow Cytometry
      • Microscopy
      Infrastructure (detailed)
      • Stirred single-use bioreactors at pilot scale (50 L/250 L)
      • Stirred, wave-mixed and orbitally shaken bioreactors at benchtop scale (0.25 L-10 L)
      • MACSQuant FlowCytometer
      • NucleoCounter NC-200
      • Single-use USP line for intensified mammalian cell cultivation (50 L)
      • Inverted phase contrast microscopes and fluorescence microscopes
      • HTS platforms based on TubeSpin and BioLector technology
      • SFR Shake flask Reader for online monitoring of shake flask cultures (PreSens Precision Sensing GmbH)
      • iLine F for measuring real-time cell critical quality attributes. (Ovizio Imaging Systems NV/SA)
      • Equipment for DSP (centrifuges, filtration systems, freeze dryer...)
      • Cedex HiRes Analyzers
      • Cedex BioAnalyzers
      • Thermo Scientific™ Invitrogen™ EVOS™ FL Auto 2 Imaging System
      Events
      Advanced training course: Cell expansion and protein expression in standard and single-use bioreactors

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