We can help you
Developing in vitro assays as close as possible to human physiology with a quantitative read-out.
- Using our own iPSCs, modify them genetically if required and differentiate them to the desired cell type.
- Using primary cells, modify them genetically if required to build the desired in vitro model.
- Developing reporter systems that are integrated into the genome, which provides a quantitative read-out.
Examples include:
- 3D epidermis model using primary keratinocytes with a reporter system for oxidative stress
- in vitro model of the blood brain barrier using brain microvascular endothelial cells derived from iPSCs.
Generating antibodies against complex membrane proteins such as GPCRs and ion channels.
- Using our rabbit cell lines to express the human protein of interest and our immunization protocol of rabbits with these cells, generating a strong immune response against the human protein in its native conformation.
Examples include:
- Antibodies against GPR137
