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To develop biotechnological production processes based on microorganisms up to pilot scale by
High throughput screening of production strains
Medium optimizations
Process parameter scouting
Multiparameter analysis
To up- and downscale cell culture-based production processes
To test as well as develop biotechnological equipment and implement it in biotechnological productions
To shorten the development time for biotechnological equipment and the number of experiments by Computational Fluid Dynamics (CFD) simulation
To verify CFD results by Particle Image Velocimetry (PIV) or shadowgraphy investigations
To plan a biotechnological production facility
To develop and test new bioreactor designs
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Competencies
Data Science
Bioprocessing
Biocatalysis
Competencies (detailed)
Biochemical engineering and bioprocess technology
Scale up and scale down of biotechnological production processes based on microbial, plant, animal and human cells (including stem cells)
Modelling of biotechnological production processes
Planning and design of biotechnological production facilities
Design of biotechnological equipment and production facilities
Computational Fluid Dynamics (CFD)
PIV and shadowgraphy
Cellular agriculture (milk proteins, plant and animal cell culture-based products)
Single-use technologies
Training
Infrastructure
Bioreactors
Cell Culture
Infrastructure (detailed)
S1 lab and technology room
Reusable and single-use bioreactors
Equipment for DSP
Automatic analyzers for substrates, metabolites and products
Cedex BioAnalyzer
Cedex HiRes Analyzer
Experimental test rig for determining key bioengineering parameters (mixing time, power input, kLa value, residence time
Shadowgraphy System for measuring particle size distribution
SOPAT probe for particle size distribution measurements (solids, droplets and bubbles)
Access to the ZHAW`s High performance computing cluster for modelling and processing purposes
Kuhner TOM (online measurement in shake flask cultivations)
HTS platforms based on TubeSpin and BioLector technology
CIP/SIP automated stirred bioreactors at pilot scale (50 L/100 L)
Biotechnet platforms
Biocatalysis and Biosynthesis
Training for Pharma / Biotech
Group leader
Dieter Eibl
Academic institution
ZHAW - Zurich University of Applied Sciences
Location
Grüentalstrasse 14, Wädenswil, Switzerland
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