Viral vector manufacturing for gene therapy

Featuring 1.5 days of theory and 2 days of hands-on practice, this training course introduces the basic principles of gene therapy and in particular the process by which viral particles can be generated and used as vectors for biomedical applications.

Cost: 3,300 CHF

Learning objectives

• Understand what gene therapy is
• Understand the types of viral vectors which are used and why
• Be able to list different available host cell lines and their main applications
• Define which bioreactor touse for adherent and suspension cells, substrate feeding, in-process controls and scale-up
• Define when to harvest and how to isolate the viral particles, freeing them of unwanted empty capsids, free DNA/RNA and host cell proteins
• Design a purification process
• Understand the regulatory requirements

Who should attend?

This course is intended for people working in a research or production environment, in USP and/ or DSP, who has a basic understanding of cell culture techniques but wishes to extend their knowledge in modern gene therapy technologies. No prior knowledge of gene or cell therapy techniques are required. Therefore the course is suitable for biologists, cell culture specialists, process designers/ developers, and anyone with an interest in gene or cell therapy.