Featuring 1.5 days of theory and 2 days of hands on practice, this advanced course covers everything from what vectors are, the different types of viral and non-viral vectors, how to produce plasmid DNA, mRNA and some typical processes used to manufacture the different vectors and their components, for different applications.
Cost: 3,300 CHF
Understanding what the need for vectors is and which properties are required for the specific application
Understanding how plasmid DNA and mRNA are produced at industrial scale
Designing a USP for the manufacture of different viral vectors
Understanding which bioreactors to use for the cultivation of packaging cell lines
Optimizing the operation of the bioreactors with respect to medium supply
Identifying the optimum conditions for transient transfection and vector titre
Defining the strategy for harvesting of the vectors
Understanding scale-up and process yield, productivity and quality (CQA)
Understanding regulatory aspects of vector manufacturing
Who should attend?
This course is intended for people working in a research or production environment, in USP and/ or DSP, who have a basic understanding of cell culture techniques but wish to extend their knowledge in areas of viral and non-viral vector manufacturing. Basic knowledge of gene or cell therapy techniques are required and the course level will be adapted according to the attendees needs. The course is suitable for biologists, cell culture specialists, process designers/ developers, and anyone with an interest in gene or cell therapy.